Claire Bénard received her Ph.D. from McGill University, supported by scholarships from NSERC and FCAR. She obtained postdoctoral fellowships from NSERC and CIHR for her training at Columbia University. She opened her lab at the Department of Neurobiology at the University of Massachusetts Medical School in 2009, where she was an Assistant Professor and then Associate Professor since 2016. Her lab has been funded by the NIH, the Ellison Biomedical Foundation, the American federation for Aging Research, and the FRQS (Fonds de recherche du Québec en Santé). She is a FRQS Junior 2 Research Scholar and a professor at the department of biological sciences at the University of Quebec at Montreal since september 2016.
Mechanisms of développement and long-term protection of the nervous system.
French topic here :
Petits cerveaux, grandes idées.
Grâce au minuscule ver C. elegans, la biologiste Claire Bénard fait progresser la recherche sur le système nerveux.
Blanchette C, Perrat P, Thackeray A, Bénard C. (2015) Glypican is a modulator of netrin-mediated axon guidance. PLOS Biology, 13(7): e1002183.
Bénard C, Blanchette C*, Recio J*, Hobert O. (2012) The secreted immunoglobulin domain proteins ZIG-5 and ZIG-8 cooperate with L1CAM/SAX-7 to maintain nervous system integrity. PLOS Genetics 8(7): e1002819.
Bénard C, Tjoe N, Boulin T, Recio J and Hobert O. (2010) The small, secreted immunoglobulin protein ZIG-3 maintains axon position in C. elegans. Genetics, 13: 917-927.
Bénard C and Hobert O. (2009) Looking Beyond Development: Maintaining Nervous System Architecture. Current Topics in Developmental Biology, 87: 175-194.
Pocock R, Bénard C, Shapiro L, Hobert O. (2008) Functional dissection of the C. elegans cell adhesion molecule SAX-7, a homologue of human L1. Molecular and Cellular Neuroscience, 37(1): 56-68.
Bénard C, Boyanov A, Hall D, Hobert O. (2006) DIG-1, a novel giant protein non-autonomously mediates maintenance of nervous system architecture. Development, 133(17): 3329-3340.
Bénard C, Kébir H, Takagi S, Hekimi S. (2004) mau-2 acts cell-autonomously to guide axonal migrations in Caenorhabditis elegans. Development, 131(23): 5947-5958
Jiang N, Bénard C, Kébir H, Shoubridge EA, Hekimi S. Human CLK2 links cell cycle progression, apoptosis and telomere length regulation. Journal of Biological Chemistry, 278(24): 21678-21684.
Bénard C, Hekimi S. Long-lived mutants, the rate of aging, telomeres and the germline in Caenorhabditis elegans. Mechanisms of Ageing and Development, 122: 869-880.
Bénard C, McCright B^, Zhang Y, Felkai S, Lakowski B, Hekimi S. (2001) The C. elegans maternal-effect gene clk-2 affects developmental timing, is essential for embryonic development, encodes a protein homologous to yeast Tel2p, and is required for telomere length regulation. Development, 128(20): 4045-4055. (*: first coauthors)
Whitfield CW, Bénard C, Barnes T, Hekimi S, Kim SK. (1999) Basolateral localization of the C. elegans EGF receptor in epithelial cells by the PDZ protein LIN-10. Molecular Biology of the Cell, 10(6): 2087-2100.
Bénard C., Takagi S., Pak J., Livingstone D., Hekimi S. (1997) Cellular and axonal migrations are misguided along both body axes in the maternal-effect mau-2 mutants of Caenorhabditis elegans. Development, 124(24): 5115-5126. (*: first coauthors)